dotbase: A Central Workspace for Data-Driven Precision Medicine
Hospital information systems are the backbone of clinical workflows. With dotbase, the next generation of this software category is emerging: Based on a more precise data foundation, the platform enhances patient care. Users in hospitals can adapt workflows to specialty-specific processes within just a few days and without any programming knowledge, by setting up custom modules and treatment pathways. This allows medical experts not only to contribute their specialized knowledge directly, but also to continuously refine the data foundation and application potential needed for personalized treatment. At the same time, dotbase smoothly fulfills the administrative and economic demands of day-to-day hospital operations.
The product development and the spin-off process of dotbase were supported by Charité BIH Innovation. The SPARK-BIH/NeuroCure Program funded and supported the implementation of one of dotbase's clinical use cases as well as the preparation and execution of a clinical feasibility study. The BIH Digital Health Accelerator Program then supported and accompanied dotbase in product and business model development as well as in the preparation of investor acquisition. on.
More Efficient Work with Clinical Data
A common problem in patient care is that data is stored in different locations, and access is often limited to certain medical departments. dotbase eliminates such data silos, allowing processes related to billing, electronic medical records, and clinical management to immediately benefit from improved data structures. At the same time, the platform standardizes care data, making it usable for research and quality assurance in the long term. The result is a dynamic system that learns and improves treatment quality and noticeably eases clinical routines.
"dotbase empowers hospitals to map even highly complex treatment pathways with unprecedented precision directly within everyday operations – without creating information barriers for billing, quality assurance, or management,"explains Jasper Mecklenburg, CEO of dotbase.
Medical Collective Intelligence Meets AI for Patient-Centered Care
dotbase integrates and structures information from a variety of sources and presents it in a clear and accessible way. The platform not only combines clinical expertise with AI-driven analyses, it also incorporates so-called patient-reported outcomes. These are data and treatment results that patients can actively contribute to, for example through surveys or wearable devices. In the future, dotbase will increasingly integrate additional AI-based features to further improve treatments and continuously reduce the administrative burden on clinical staff.
From Neurology to Broad Hospital Adoption
The founding team, led by Jasper Mecklenburg (CEO) and Andrea Kreichgauer (CTO), developed dotbase in the Section for Movement Disorders and Neuromodulation (Prof. Dr. Andrea Kühn) to optimize documentation for deep brain stimulation in Parkinson’s patients. Interest from other disciplines quickly followed: Today, dotbase already supports more than ten medical specialties – including oncology and psychiatry.
"Over the long term, dotbase enables a significant reduction in redundant documentation by capturing patient data in a central and efficient way," says Prof. Dr. Maria Margarete Karsten, leading senior physician in Senology at Charité. "This eases our day-to-day clinical workload and allows us to focus more on the individual care of our breast cancer patients."
Several departments at Charité are already using dotbase successfully. Starting at the end of 2025, the platform will be rolled out across the entire hospital. At the same time, it will also be introduced at other university hospitals across Germany.
"dotbase demonstrates how the BIH is paving the way for patient-centered medical care," says Prof. Christopher Baum, Chair of the BIH Board of Directors and Chief Translational Research Officer of Charité – Universitätsmedizin Berlin. "This new platform enables efficient knowledge aggregation and fosters collaboration between medical professionals and patients. We hope this will significantly improve the quality of care."
