New method facilitates identification of cell-type specific genes in single-cell data

“Outer Radial Glia” (oRG) cells are nervous system stem cells that are instrumental for the development of the human cortex and have been challenging to produce in the lab. Now, a team of Max Planck researchers from Berlin succeeded in generating…

How do cancer cells differ from healthy cells? A new machine learning algorithm called “ikarus” knows the answer, reports a team led by MDC bioinformatician Altuna Akalin in the journal "Genome Biology". The AI program has found a gene signature…

In modern society, the incidence of neurodegenerative diseases such as Alzheimer's and Parkinson's is steadily increasing. Emerging symptoms range from memory and movement disorders to the inability to lead a self-determined life. These changes place…

A technique called Deep Visual Proteomics helps shed new light on cancer cell properties, a German-Danish team now reports in “Nature Biotechnology”. Fabian Coscia co-developed the new method and will further refine it at the MDC – with the aim of…

Pediatric oncologist Prof. Dr. Anton Henssen, from Charité – Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), and a group of researchers from the US and the UK have won funding for a Cancer…

A cellulose based material could be useful for medical applications such as wound sealant

The ability to perform complex movements is vital for animals. A team led by MDC researcher Niccolò Zampieri has now described in the journal “Current Biology” how little-studied sensory neurons near the central canal in the spinal cord help regulate…

Four collaborative projects, including one infrastructure project participate in framework program

Effective July 1, 2022, Ludovic Vallier will take up the W3 Einstein Strategic Professorship for Stem Cells in Regenerative Therapies at the Berlin Institute of Health at Charité (BIH). Vallier is an expert in pluripotent stem cells and organoids. He…